Texas is arguably the most frightening place in the country for families of transgender children. The state’s GOP leadership, often in partnership with the Trump administration, has threatened to take children away from their families, chased physicians out of the state and attacked children’s hospitals. Fearing for their safety, many families have fled. In 2022, one mother of a transgender daughter warned, “This is a crisis … we have political refugees in the U.S., leaving with whatever they can fit in their car.”
As part of this ongoing focus on transgender youth, the state, in partnership with the Justice Department, held a yearslong investigation of Texas Children’s Hospital, focusing on the medical center’s treatment of transgender youth. On Friday, the DOJ and Texas Children’s Hospital announced they had reached a settlement.
Detransition can mean many things, ranging from regretting treatment to being forced by the state to stop treatment against your will.
While denying any wrongdoing, the hospital agreed to pay $10 million and fire five physicians who provided gender-affirming care to adolescents. The settlement also includes an unexpected provision: The hospital will fully fund a “detransition clinic.”
What that means remains to be seen. Detransition can mean many things, ranging from regretting treatment to being forced by the state to stop treatment against your will. Texas Attorney General Ken Paxton said the detransition clinic will provide care free of charge for its first five years of operation, adding that the hospital’s $10 million settlement money will go toward covering costs from the hospital billing Texas Medicaid for gender-affirming services performed for patients.
As a physician-scientist, I am always in favor of expanding support for patients and collecting more research. I genuinely hope this new clinic will support young people and advance the science of pediatric gender care. But we need to be honest about what the science shows: When offered under current guidelines, regret following gender-affirming medical care for adolescent gender dysphoria is rare. In many states, “detransition” is not a personal medical decision; it is forced upon people by the law.
A recent longitudinal study from Princeton examined regret among 220 adolescents who underwent gender-affirming medical interventions such as pubertal suppression or gender-affirming hormones (estrogen or testosterone). The research team followed these adolescents a mean 4.8 years after pubertal suppression and a mean 3.4 years after gender-affirming hormones. Only 4% expressed any kind of regret. Among those, half continued treatment, suggesting the benefits outweighed the things they regretted. This regret rate is far lower than other areas of pediatric medicine. For example, 38% of caregivers report some level of regret following their children’s surgery for congenital adrenal hyperplasia.








